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Osteoporosis – an unfortunate condition that can spoil one’s life quality significantly due to numerous reasons. People experience trouble moving freely and sometimes can’t perform even the easiest tasks, and exercising must be left in the past not to worsen their condition. However, all of these problems can be easily left in the past as more and more solutions occur in the medical sphere to treat osteoporosis and significantly improve one’s life quality.
When speaking about effective injectables to deal with this disease, Prolia and Reclast are the first ones that come to mind. Even though they have the same goal (to relieve osteoporosis complications), they still have some essential differences that should be known and considered before starting the treatment. Today, we are going to discuss these products in more detail so people have a better understanding of their doctors’ recommendations. We are sure some of your friends and colleagues may find this article useful; don’t hesitate to share it after you finish reading it!
Prolia’s generic name is Denosumab, and it’s used to prevent and cure osteoporosis in women during the postmenopausal period. It belongs to the monoclonal antibody class and guarantees a long-lasting improvement for patients with different stages of bone problems.
This injectable type is perfect for treating and preventing osteoporosis. It also demonstrated excellent results in metastatic bone cancer and bone cell tumor prevention, which is rather beneficial for overall bone strength. Medication-induced bone loss is another problem targeted with this drug. According to studies, this product’s effect is typically better on women than men.
To buy Prolia, you must either be an educated medical professional or have a valid prescription from your doctor. The procedure must be performed in the doctor’s office by a specialist with perfect knowledge of the administration technique and Prolia’s working principle (it’s required to calculate the correct dose).
The main issue with osteoporosis is a significant decrease in a natural inhibitor of RANKL (it’s a growth factor). Prolia, as a monoclonal antibody, connects to RANKL and makes osteoclasts production slower. As a result, a balance between bone breakdown and bone growth is achieved, reducing their degradation significantly.
Different drug classes may lead to various body reactions, and it’s essential to be aware of those to understand when it’s time to see a doctor. Among the most symptoms is joint and muscle pain in the legs and arms. Increased risk of inflammations and allergic reactions is also possible as RANKL may affect the immune system.
Among rarer side effects people experience is low calcium in the blood due to bone rebuild, so patients with vitamin D and blood calcium deficiency can use Prolia to improve their bone density. Osteonecrosis of the jaw bone (mainly after dental procedures) and atypical femur fractures have been reported.
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Reclast is an effective injectable for severe osteoporosis; its active substance is zoledronic acid, which is vital to increase bone density. Here are some of the important details you should know about this brand.
This product is helpful for a number of bone problems: osteoporosis, high blood calcium caused by cancer and Paget’s disease, bone breakdown, and others. A few injections are typically required to see the beneficial effect, and the procedure should be repeated once every few months to continue the results.
Only a doctor may prescribe this product to an individual, as Reclast doesn’t belong to over-the-counter medications. Its administration should also be performed in the clinic according to the previously discussed treatment plan.
Zoledronic acid belongs to the bisphosphonate drugs class, among the most intense medications for osteoporosis. The solution is supposed to get to the places of high bone turnover to pause bone resorption. It increases bone density, so it’s not damaged so easily because of the triggers.
Most patients experience minor inconveniences, such as swelling and increased muscle sensitivity after the injection session. People also often notice fever, increased blood pressure, joint pain, and extreme tiredness.
Regarding severe adverse reactions, low calcium in the blood, kidney damage, and jaw osteonecrosis. That’s the main reason why this product is not recommended for individuals with known kidney dysfunction or low blood calcium; they have a high risk of experiencing severe complications and adverse effects.
To understand the primary differences between the two brands, it is essential to understand their main tasks as osteonecrosis infusions.
Prolia works by covering osteoclasts (cells that eventually break the bones) with RANKL; by doing so, it slows down its formation and makes it impossible for the disease to progress. Bones density and strength on both outer and inner layers are improved this way, and patients experience significant relief for up to six months.
Reclast is a bisphosphonate that pauses osteoclasts that break down and reabsorb the bones, as well as slow down calcium release by the skeleton induced by tumors. The effect lasts up to two years, but a maintenance treatment is sometimes required to keep up with the results.
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Osteoporosis is a condition that must be treated on time to prevent the disease from worsening. Prolia and Reclast are effective products designed specifically for this task! They help avoid bone structure damage, pause the condition, and make it easier for people to live their lives to the fullest despite their health issues. To select the right brand, it’s essential to consult with a doctor and discuss the details of one’s condition; without it, the injectable cannot be purchased.
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