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Profhilo vs. Sculptra: A Big Comparison

Author: Brenda Adams

Among a wide variety of dermal fillers available in the aesthetic medicine market these days, Profhilo and Sculptra definitely stand out. They both belong to the most advantageous cosmetic injectables for the overall rejuvenation and enhancement of a patient’s appearance.

But which dermal filler brand, Profhilo or Sculptra, should you choose to achieve the best possible result? Hopefully, the article below will help you to find an answer to this question. Let us go through this big comparison of the two dermal fillers together!

Young Blonde Woman choose between Profhilo and Sculptra

A Few Words On Dermal Fillers

Before delving into the comparison of Profhilo and Sculptra, how about briefly talking about dermal fillers? What are they? What types of dermal fillers are there? And what are the most popular dermal filler brands available in the aesthetic medicine market these days?

Above anything else, it is worth mentioning that dermal fillers are injectable treatments used for the creation of a refreshed appearance by means of addressing the first signs of aging, starting from facial volume loss and ending with facial wrinkles.

Depending on the main active substance employed in the composition of dermal fillers, they might be divided into several types, such as hyaluronic acid fillers, calcium hydroxyapatite fillers, or poly-L-lactic acid fillers.

While the most popular brands of soft tissue fillers are:

Each above-mentioned soft tissue filler brand has its own peculiarities and indications. While some of them effectively stimulate collagen production, others tighten the sagging skin or promote skin hydration.

General Information on Profhilo and Sculptra

Both Profhilo and Sculptra are non-surgical skin treatments used to improve skin elasticity, hydration, and smoothness. In other words, they improve skin quality in a minimally invasive, effective, and durable way.

Below, you will be able to check out the general information on the peculiarities of Profhilo and Sculptra treatment sessions. Check out the details on their manufacturers, compositions, indications, and expected results.

Profhilo Treatment

Profhilo is a brand of injectable treatment solutions manufactured in Italy by IBSA. The main active substance in the composition of Profhilo is hyaluronic acid of both high and low molecular weight.

According to its treatment protocol, Profhilo should be injected beneath a patient’s skin with the help of a fine gauge needle. As soon as it is done, a product starts to deeply hydrate the skin tissues by stimulating collagen production.

More precisely, Profhilo is an advantageous skin treatment used to restore the more youthful appearance of a patient by effectively addressing the following issues:

  • Mild to deep wrinkles all over the facial oval;
  • Facial sagging of the skin;
  • Poorly defined facial contours;
  • And so on.

It is also worth mentioning that a typical Profhilo treatment protocol usually assumes two sessions performed about four weeks apart. With their help, most patients manage to achieve their desired results and maintain them for up to one year.

When looking for a reliable place to order Profhilo online, check out what MedEuroStore offers. Here, you will be able to find a broad range of brand-name dermal fillers for affordable prices.

Sculptra Treatment

Sculptra is a brand of injectable treatment solutions manufactured by Dermik Laboratories, a branch of a global pharmaceutical company Aventis Dermatology. The main active substance in its composition is poly-L-lactic acid.

As the treatment protocol of Sculptra suggests, it should be administered beneath a patient’s skin by means of employing a fine gauge needle. This way, the product has the power to function as a powerful collagen stimulator.

Moreover, it is important to state that Sculptra manages to accelerate collagen stimulation and create skin rejuvenation by taking care of the following aesthetic concerns:

  • Facial fine lines and wrinkles;
  • Lack of skin tightening and skin firmness;
  • Absence of the youthful glow of the skin;
  • And so on.

In most cases, it is possible to administer Sculptra beneath a patient’s skin in a series of multiple sessions (their exact number should be defined by a certified healthcare provider based on the individual peculiarities of each patient). They create long-lasting results with a duration of up to two years.

MedEuroStore is one of the most beneficial online suppliers of dermal fillers. Here, you will be able to purchase Sculptra and other FDA-approved products advantageously.

A Comparison of Profhilo vs. Sculptra

After delving into the peculiarities of the treatment process that employs Profhilo and Sculptra, it is high time to discuss the similarities and differences between them.

Although both products aim to promote a patient’s skin health in a safe, effective, and durable way, they are not identical. Below, you will be able to compare and contrast Profhilo and Sculptra treatments.


Let us start with a discussion of the similarities between Profhilo and Sculptra injections. Here are the main things that unite both aesthetic treatments.

#1. Aesthetic Medicine Category

Both Profhilo and Sculptra belong to the aesthetic medicine category of dermal fillers. While being responsible for skin rejuvenation and enhancement with no to minimal downtime, they should be injected in pretty similar ways.

#2. Indications

Similar to any other treatment from the category of dermal fillers, Profhilo and Sculptra do a great job when it comes to the treatment of skin sagging, restoration of skin attractiveness, and improvement of skin smoothness. They also are optimal solutions to stimulate new collagen production and target specific concerns of each patient.

#3. Contraindications

Neither Profhilo nor Sculptra aims to smooth lines, restore volume, or fight collagen loss in patients who live with serious chronic diseases, have allergic reactions to any components of dermal fillers, or are pregnant or breastfeeding.

#4. Possible Side Effects

In most cases, Profhilo and Sculptra do not cause any adverse reactions after being injected into the human body. They might lead to temporary skin irritation around the injection site (including redness, itching, or swelling), which tends to fade away in a couple of days after the treatment.


Now, how about putting Sculptra vs. Profhilo side to side and discussing the main differences between them? Here are the main things that differentiate both aesthetic treatments.

#1. Composition

Profhilo is a soft tissue filler based on hyaluronic acid. Sculptra, in turn, is a special treatment that employs poly-L-lactic acid as its main active substance. Both hyaluronic acid and poly-L-lactic acid are effective in restoring volume and stimulating collagen production in the treatment area. Still, they do so in pretty different ways.

#2. Duration of Action

One of the key benefits of Sculptra is its long-lasting duration of action. Depending on the individual peculiarities of each patient, the effect of the product might last up to two years. Profhilo, in turn, tends to create results that equal one year on average.

#3. Target Areas

While Sculptra primarily stimulates collagen production around the facial oval of a patient, Profhilo is also frequently used as a treatment for the skin on a patient’s face, neck, and hands. Still, the exact treatment site for both treatments should be discussed with a healthcare provider.

#4. Working Principle

Even though both the Profhilo and Sculptra treatment processes assume the acceleration of the natural production of collagen, the Profhilo treatment process also functions as a powerful skin moisturizer that effectively attracts moisture to the skin cells.

A Bottom Line

All in all, Profhilo and Sculptra belong to non-surgical skin treatments with natural-looking results. Despite having a number of differences, they both are characterized by high-quality composition, strong effectiveness, and long-lasting duration of action.

So, we are sure that you are going to remain satisfied, no matter which product you are going to choose!

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